It is painful to see sentient beings we love not only suffering now, but also continuing to accumulate causes of future suffering.
At times like this, it is important to remember that we are not impotent. Whatever good we do is of universal benefit.
Even if particular individuals will not accept our kindness and compassion, we can reduce their suffering indirectly, by helping others. By improving the quality of the environment through our virtuous acts, everyone benefits.
When we give love to those who accept it, even those who reject it are embraced.